Flagyl ER Dosage: Quick Guide

If you’ve been prescribed Flagyl ER, you probably want to know exactly how much to take and when. Flagyl ER is the extended‑release form of metronidazole, a medication used for infections like bacterial vaginosis, trichomoniasis, and certain GI bugs. The good news is the dosing schedule is straightforward once you understand the basics.

Standard Dosing Recommendations

For most adult infections, the typical Flagyl ER dose is 500 mg taken twice a day (every 12 hours). This means you’ll have a pill in the morning and another in the evening, usually with food to avoid stomach upset. The treatment length varies:

  • Gynecologic infections (bacterial vaginosis, trichomoniasis): 7 days.
  • GI infections (Clostridioides difficile, amoebic dysentery): 10‑14 days, sometimes longer if your doctor says so.
  • Skin or bone infections: often 10‑14 days, but follow the exact plan your doctor gave you.
If your prescriber wrote a different dose—like 750 mg once daily—that’s because of a specific condition or kidney function. Always follow the exact numbers on the prescription label.

Special Situations & Safety Tips

Some people need adjustments. If you have liver disease, your doctor might lower the dose because metronidazole is processed in the liver. Kidney problems can also affect how long the drug stays in your system, so a dose cut may be needed.

Alcohol is a big no‑no while you’re on Flagyl ER. Even a single drink can cause nausea, vomiting, flushing, and a rapid heartbeat. The safest move is to avoid alcohol completely during treatment and for at least 48 hours after the last pill.

Watch out for common side effects such as a metallic taste, mild nausea, or a headache. These usually go away on their own. If you notice severe belly pain, dark urine, or a rash, call your doctor right away—those could be signs of a rare but serious reaction.

Never skip a dose, but if you do, take it as soon as you remember—unless it’s almost time for the next one. In that case, just skip the missed pill; don’t double up. Doubling can increase the risk of stomach irritation and other side effects.

Store Flagyl ER at room temperature, away from moisture and heat. Keep the bottle tightly closed and out of reach of children.

Finally, finish the whole course even if you feel better after a few days. Stopping early can let the infection come back and may make it harder to treat later.

With the right dose, timing, and a few safety habits, Flagyl ER can clear up your infection without a hitch. If something feels off, reach out to your healthcare provider—better safe than sorry.

  • Stéphane Moungabio
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Flagyl ER: Uses, Dosage, Side Effects & Safety Guide (2025)

Everything you need to know about Flagyl ER - what it treats, how to take it, common side effects, safety tips and Australian prescription rules.

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