If you suffer from heartburn or acid reflux, you’ve probably heard of PPIs. These are medicines that lower stomach acid and give your gut a break. While many PPIs need a prescription, several are now sold over the counter (OTC) in places like the UK and Australia.
Proton pump inhibitors block the enzyme that makes stomach acid. By doing so, they reduce the amount of acid that reaches your esophagus. The result? Less burning, fewer night‑time symptoms, and a lower chance of damage to your throat.
The most common OTC PPI is omeprazole, sold under brand names like Prilosec. In 2025 you’ll also see generic esomeprazole (the ingredient in Nexium) popping up on reputable online pharmacies. These pills usually come in 20 mg doses, taken once a day before breakfast.
When you shop for an OTC PPI, look for these signs of a safe purchase:
If you’re based in Australia, the PBS may cover some OTC PPIs when a doctor signs a short script. Check local guidelines before ordering online.
Most people feel better within 3‑4 days, but give it at least two weeks for full effect. Don’t mix PPIs with antacids at the same time – space them out by an hour to avoid reduced absorption.
Side effects are rare but can include headache, mild diarrhea, or a slight metallic taste. If you notice severe stomach pain or persistent nausea, stop the pill and talk to a pharmacist.
Remember, OTC PPIs are great for occasional heartburn, but they’re not meant for long‑term use without medical supervision. Chronic reflux may need a prescription strength dose or an investigation into underlying causes.
Bottom line: Choose a reputable source, stick to the recommended dose, and watch how quickly your symptoms improve. With the right OTC PPI, you can ditch the burning feeling and get back to enjoying meals without worry.
Looking for cheap generic Prilosec? See UK-safe ways to order omeprazole online, real price ranges, how to avoid fakes, dosing basics, and when to talk to your GP.
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